Eideard

On which problems should we focus research in medicine and the biological sciences? There is a strong argument for tackling the diseases that kill the most people – diseases like malaria, measles, and diarrhea, which kill millions in developing countries, but very few in the developed world.

Developed countries, however, devote most of their research funds to the diseases from which their citizens suffer, and that seems likely to continue for the foreseeable future. Given that constraint, which medical breakthrough would do the most to improve our lives..?

In developed countries, aging is the ultimate cause of 90% of all human deaths; thus, treating aging is a form of preventive medicine for all of the diseases of old age. Moreover, even before aging leads to our death, it reduces our capacity to enjoy our own lives and to contribute positively to the lives of others. So, instead of targeting specific diseases that are much more likely to occur when people have reached a certain age, wouldn’t a better strategy be to attempt to forestall or repair the damage done to our bodies by the aging process?

Aubrey De Grey believes that even modest progress in this area over the coming decade could lead to a dramatic extension of the human lifespan. All we need to do is reach what he calls “longevity escape velocity” – that is, the point at which we can extend life sufficiently to allow time for further scientific progress to permit additional extensions, and thus further progress and greater longevity. Speaking recently at Princeton University, de Grey said: “We don’t know how old the first person who will live to 150 is today, but the first person to live to 1,000 is almost certainly less than 20 years younger…”

We still need to pose the ethical question: Are we being selfish in seeking to extend our lives so dramatically? And, if we succeed, will the outcome be good for some but unfair to others?

People in rich countries already can expect to live about 30 years longer than people in the poorest countries. If we discover how to slow aging, we might have a world in which the poor majority must face death at a time when members of the rich minority are only one-tenth of the way through their expected lifespans.

No doubt De Grey has interesting conversations with Ray Kurzweil. Peter Singer does a nice job of masking his own position on the questions he asks of De Grey. And he offers each of us a chance to scratch that particular curiosity itch on our own.

Regular readers of this blog know my answer – no doubt. Go for it!