Eideard

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Posts Tagged ‘anti-oxidant

Onions: a natural alternative to artificial preservatives

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Some components of the onion have antioxidant and antimicrobial properties, making it possible to use this bulb for food preservation. This is demonstrated by researchers from the Polytechnic University of Cataluña (UPC) and the University of Barcelona (UB) in a study that has just been published…

The study, that has just been published by the International Journal of Food Science and Technology, shows that the flavonoids of onion, in addition to having beneficial properties for health, increase the life of foods, and so “they are a natural alternative to artificial additives used in the food industry.” Flavonoids are phenolic compounds (with the phenol group) which are synthesized by plants.

The results confirm that, especially the yellow variety, is “a good source of these types of substances, and there is a positive correlation between the presence of flavonoids and their antioxidant capacity…”

Previous studies indicate that flavonoids have beneficial effects for health due to their antioxidant, anti-inflammatory, cardioprotective, vasodilatory and anti-carcinogenic properties, making it of special interest in the prevention of chronic illnesses, such as cardiovascular illnesses, and some types of cancer…

The onion (Allium cepa) is one of the most cultivated and consumed vegetables on the planet (around 66 million tonnes in 2008, of which 1.1 million were produced in Spain, especially in Castilla-La Mancha), and one of the main ingredients of the Mediterranean diet.

Certainly is a significant part of my diet. Most of my recipes start with “brown an onion”…

Written by eideard

April 16, 2010 at 3:00 pm

Vitamin C surprise – helps reprogram adult cells into stem cells

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Famous for its antioxidant properties and role in tissue repair, vitamin C is touted as beneficial for illnesses ranging from the common cold to cancer and perhaps even for slowing the aging process. Now, a study published online…in the journal Cell Stem Cell uncovers an unexpected new role for this natural compound: facilitating the generation of embryonic-like stem cells from adult cells.

Over the past few years, we have learned that adult cells can be reprogrammed into cells with characteristics similar to embryonic stem cells by turning on a select set of genes. Although the reprogrammed cells, called induced pluripotent stem cells (iPSCs), have tremendous potential for regenerative medicine, the conversion is extremely inefficient.

Dr. Duanqing Pei and colleagues measured the production of reactive oxygen species or ROS during reprogramming and discovered a potential link between high ROS and low reprogramming efficiency. They became particularly interested in antioxidants, hypothesizing that they might suppress ROS and cell senescence, which seems to be a major roadblock for the generation of iPSCs.

The researchers found that adding vitamin C, an essential nutrient that is abundant in citrus fruits, enhanced iPSC generation from both mouse and human cells. Vitamin C accelerated gene expression changes and promoted a more efficient transition to the fully reprogrammed state. Somewhat to their surprise, they found that other antioxidants do not have the same effect, but vitamin C does seem to act at least in part through slowing cell senescence.

Our results highlight a simple way to improve iPSC generation and provide additional insight into the mechanistic basis of reprogramming,” concludes Dr. Pei. “It is also of interest that a vitamin with long-suspected anti-aging effects has such a potent influence on reprogramming, which can be considered a reversal of the aging process at the cellular level. It is likely that our work may stimulate further research in this area as well.”

Stimulates the hell out of my curiosity. That’s for sure.

I always appreciate the interlocking dialectic of multiple scientific disciplines. Often, you find new directions, new solutions you hadn’t even been looking for.

Written by eideard

December 30, 2009 at 12:00 pm

Whole grain cereals, popcorn are rich in antioxidants

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In a first-of-its kind study, scientists reported today at the 238th National Meeting of the American Chemical Society (ACS) that snack foods like popcorn and many popular breakfast cereals contain “surprisingly large” amounts of healthful antioxidant substances called “polyphenols.”

Polyphenols are a major reason why fruits and vegetables — and foods like chocolate, wine, coffee, and tea — have become renowned for their potential role in reducing the risk of heart disease, cancer, and other diseases.

Until now, however, no one knew that commercial hot and cold whole grain cereals — regarded as healthful for their fiber content — and snack foods also were a source of polyphenols.

Early researchers thought the fiber was the active ingredient for these benefits in whole grains, the reason why they may reduce the risk of cancer and coronary heart disease,” said Joe Vinson, Ph.D., who headed the new study. “But recently, polyphenols emerged as potentially more important. Breakfast cereals, pasta, crackers, and salty snacks constitute over 66 percent of whole grain intake in the U.S. diet.”

Vinson, a chemist at the University of Scranton in Pennsylvania, said “We found that, in fact, whole grain products have comparable antioxidants per gram to fruits and vegetables. This is the first study to examine total phenol antioxidants in breakfast cereals and snacks, whereas previous studies have measured free antioxidants in the products…”

The whole grain cereal with the most antioxidants are made with wheat, with corn, oats and rice cereals following in descending order, according to Vinson. He also noted that raisin bran has the highest amount of antioxidants per serving, primarily due to the raisins.

Bran cereals made from wheat overall do not have more antioxidants than wheat cereals, though they do have more fiber, he said. In other findings, he said that whole grain flours are very high in antioxidants; whole grain snacks have slightly lower levels of antioxidants than cereals; of snacks, popcorn has the highest level of antioxidants; and there is a wide variation in the amount of antioxidants in each class of cold cereal.

OK, so when you’re preparing your popcorn – turn it into a thoroughly Mediterranean snack. Instead of drizzling melted butter over it, put a couple ounces of a good virgin olive oil in a microwave-capable glass measuring cup – along with a few finely chopped garlic cloves. Microwave it for 5 minutes at about one-third power.

Pour that over your popcorn along with a minimum of salt – and Rock On!

Written by eideard

August 21, 2009 at 10:00 pm

How garlic gets to be good for you

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Daylife/AFP/Getty Images

It was widely believed that the organic compound, allicin – which gives the pungent vegetable its aroma and flavour – acts as an antioxidant. But until now it hasn’t been clear how allicin works, or how it stacks up compared to more common antioxidants such as Vitamin E and coenzyme Q10, which stop the damaging effects of radicals.

We didn’t understand how garlic could contain such an efficient antioxidant, since it didn’t have a substantial amount of the types of compounds usually responsible for high antioxidant activity in plants, such as the flavanoids found in green tea or grapes,” says Dr. Derek Pratt. “If allicin was indeed responsible for this activity in garlic, we wanted to find out how it worked.”

The research team questioned the ability of allicin to trap damaging radicals so effectively, and considered the possibility that a decomposition product of allicin may instead be responsible. Through experiments with synthetically-produced allicin, they found that sulfenic acid produced when the compound decomposes rapidly reacts with radicals.

“While garlic has been used as a herbal medicine for centuries and there are many garlic supplements on the market, until now there has been no convincing explanation as to why it is beneficial,” says Dr. Pratt. “I think we have taken the first step in uncovering a fundamental chemical mechanism which may explain garlic’s medicinal benefits.”

Interesting to learn that a variable like the rate of decomp governs the production of sulfenic acid. Raises questions about imparting a similar mechanism to other alliums? We’re getting to where genomics has such capabilities.

Written by eideard

January 31, 2009 at 2:00 pm

Posted in Health, Science

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