Posts Tagged ‘George Whitesides’
Octopus-like flexible robot crawls through tight spaces

Harvard scientists have built a new type of flexible robot that is limber enough to wiggle and worm through tight spaces.
It’s the latest prototype in the growing field of soft-bodied robots. Researchers are increasingly drawing inspiration from nature to create machines that are more bendable and versatile than those made of metal.
The Harvard team, led by chemist George M. Whitesides, borrowed from squids, starfish and other animals without hard skeletons to fashion a small, four-legged rubber robot that calls to mind the clay animation character Gumby…
The Harvard project, funded by the Pentagon’s research arm…took two months to construct, is 5 inches (12.7 centimeters) long. Its four legs can be separately controlled by pumping air into the limbs, either manually or via computer. This gives the robot a range of motions including crawling and slithering.
The researchers tested the robot’s flexibility by having it squirm underneath a pane of glass just three-quarters of an inch from the surface.
Scientists maneuvered the robot through the tiny gap 15 times using a combination of movements. In most cases, it took less than a minute to get from side to side.
Researchers eventually want to improve the robot’s speed, but were pleased that it did not break from constant inflation and deflation.
“It was tough enough to survive,” said Harvard postdoctoral fellow Robert Shepherd, adding that the robot can traverse on a variety of surfaces including felt cloth, gravel, mud and even Jell-O.
There were drawbacks. The robot is tethered to an external power source and scientists need to find a way to integrate the source before it can be deployed in the real world…
I love this stuff. Of course, I can see the first battlefield simulation being defeated by a Jack Russell terrier.
Or the first real-life use searching for earthquake survivors in a collapsed building? I can hear some poor bugger trapped in the rubble screaming in panic when he sees a version of this wriggling towards him in the dust and darkness.
Shrinking the size of tests – and their cost – down to pennies

While other scientists successfully shrank beakers, tubes and centrifuges into diagnostic laboratories that fit into aluminum boxes that cost $50,000, George Whitesides had smaller dreams. The diagnostic tests designed in Dr. Whitesides’s Harvard University chemistry laboratory fit on a postage stamp and cost less than a penny.
His secret? Paper.
His colleagues miniaturized diagnostic tests so they could move into the field with tiny pumps and thread-thin tubes. Dr. Whitesides opted for a more novel approach, reasoning that a drop of blood or urine could wick its way through a square of filter paper without any help.
And if the paper could be etched with tiny channels so that the drop followed a path, and if that path were mined with dried proteins and chemically triggered dyes, the thumbnail-size square could be a mini-laboratory — one that could be run off by the thousands on a Xerox machine.
Diagnostics for All, the private company Dr. Whitesides founded four years ago here in Boston’s Brighton neighborhood to commercialize his inspirations, has already created such a test for liver damage. It requires a single drop of blood, takes 15 minutes and can be read by an untrained eye: If a round spot the size of a sesame seed on the paper changes to pink from purple, the patient is probably in danger.
Using paper in diagnostic tests is not entirely new. It soaks up urine in home pregnancy kits and blood in home diabetes kits. But Dr. Whitesides has patented ways to control the flow through multiple layers for ever-more-complex diagnoses. His test has proved more than 90 percent accurate on blood samples previously screened by the laboratory of Beth Israel Deaconess Medical Center, a Harvard teaching hospital, said Una S. Ryan, chief executive of Diagnostics for All…
The initial target audience is AIDS patients with tuberculosis who must take powerful cocktails of seven or more drugs. Some drugs damage the liver, and deaths from liver failure are 12 times as common among African AIDS patients as among American ones, Dr. Ryan said, because current liver tests are expensive and require tubes of blood…
RTFA. Truly worthwhile effort, starting with grants from the Bill and Melinda Gates foundation and carrying through to government assistance both sides of the pond.
Taking the cost of tests from dollars to pennies makes them affordable in the 3rd World – as well as the growing pool of poverty in the industrial West. Many examples, many goals already met. The sort of medical research that doesn’t make billions for pharmaceutical giants; but, helps human beings worldwide.




