Posts Tagged ‘Harvard’
Octopus-like flexible robot crawls through tight spaces

Harvard scientists have built a new type of flexible robot that is limber enough to wiggle and worm through tight spaces.
It’s the latest prototype in the growing field of soft-bodied robots. Researchers are increasingly drawing inspiration from nature to create machines that are more bendable and versatile than those made of metal.
The Harvard team, led by chemist George M. Whitesides, borrowed from squids, starfish and other animals without hard skeletons to fashion a small, four-legged rubber robot that calls to mind the clay animation character Gumby…
The Harvard project, funded by the Pentagon’s research arm…took two months to construct, is 5 inches (12.7 centimeters) long. Its four legs can be separately controlled by pumping air into the limbs, either manually or via computer. This gives the robot a range of motions including crawling and slithering.
The researchers tested the robot’s flexibility by having it squirm underneath a pane of glass just three-quarters of an inch from the surface.
Scientists maneuvered the robot through the tiny gap 15 times using a combination of movements. In most cases, it took less than a minute to get from side to side.
Researchers eventually want to improve the robot’s speed, but were pleased that it did not break from constant inflation and deflation.
“It was tough enough to survive,” said Harvard postdoctoral fellow Robert Shepherd, adding that the robot can traverse on a variety of surfaces including felt cloth, gravel, mud and even Jell-O.
There were drawbacks. The robot is tethered to an external power source and scientists need to find a way to integrate the source before it can be deployed in the real world…
I love this stuff. Of course, I can see the first battlefield simulation being defeated by a Jack Russell terrier.
Or the first real-life use searching for earthquake survivors in a collapsed building? I can hear some poor bugger trapped in the rubble screaming in panic when he sees a version of this wriggling towards him in the dust and darkness.
Print your own Chandra calendar
Print your own 2012 Chandra calendar with spectacular images from the past year. Featured objects include supernova remnants, galaxies in various shapes & sizes and star clusters in our very own Milky Way. Available as a 12-page full color PDF in 17×11″ sizes. Individual months may also be downloaded separately.
Glorious, gorgeous, send a link to your favorite flat-earther.
IgNobel prize awards once again precede the more serious variety
The Peace Prize to Vilnius’ mayor – who solved the problem of illegal parking
Prognosticators who predicted the end of the world and got it wrong, scientists who built a wasabi fire alarm, and researchers who studied how the urge to urinate affects decision-making were among the winners of spoof Ig Nobel prizes on Thursday.
The annual prizes, meant to entertain and encourage scientific research, are awarded by the Journal of Improbable Research as a whimsical counterpart to the Nobel Prizes, which will be announced next week.
Ig Nobels also went to researchers who found that the male buprestid beetle likes to copulate with Australian beer bottles called stubbies, and researchers who showed why discus throwers become dizzy and hammer throwers do not.
Former winners of the real Nobel prizes hand out the prizes at a ceremony held at Harvard University in Massachusetts…
Peter Snyder, a professor of Neurology at Brown University in Providence, Rhode Island, was part of two research teams who won the Medicine Prize for studying how the urge to urinate affects decision-making.
Snyder’s team set up an experiment in which volunteers did computer tests and then periodically drank 250 ml (about 8 ounces) of water as the scientists measured the effects of the volunteers’ gradually swelling bladders on attention and working memory. The aim was to see who could last the longest before bolting for the toilet.
The study found that attention and working memory suffer when you are so focused on having to pee.
“When you gotta go, you gotta go,” Snyder said…
– John Perry of Stanford University for his Theory of Structured Procrastination, which holds procrastinators can be motivated to do important things as long as they are doing them as a way of avoiding something even more important…
– Anna Wilkinson of the University of Lincoln in the United Kingdom, Natalie Sebanz of Radboud University Nijmegen in the Netherlands and others for their study that found no evidence of contagious yawning in red-footed turtles…
– Karl Halvor Teigen of the University of Oslo, Norway, for trying to understand why, in everyday life, people sigh.
– Americans Dorothy Martin who predicted the world would end in 1954; Pat Robertson who predicted the world would end in 1982; Elizabeth Clare Prophet who predicted the world would end in 1990; and Harold Camping who predicted the world would end on September 6, 1994, and on October 21, 2011; Lee Jang Rim of Korea who predicted the world would end in 1992; Shoko Asahara of Japan who predicted the world would end in 1997; Credonia Mwerinde of Uganda who predicted the world would end in 1999 — for teaching the world to be careful when making mathematical assumptions and calculations.
It takes a profound sense of humor for any dedicated scientist to work at serious tasks in so many societies mostly founded upon absolute nonsense.
Here’s a list of all this year’s winners.
Shrinking the size of tests – and their cost – down to pennies

While other scientists successfully shrank beakers, tubes and centrifuges into diagnostic laboratories that fit into aluminum boxes that cost $50,000, George Whitesides had smaller dreams. The diagnostic tests designed in Dr. Whitesides’s Harvard University chemistry laboratory fit on a postage stamp and cost less than a penny.
His secret? Paper.
His colleagues miniaturized diagnostic tests so they could move into the field with tiny pumps and thread-thin tubes. Dr. Whitesides opted for a more novel approach, reasoning that a drop of blood or urine could wick its way through a square of filter paper without any help.
And if the paper could be etched with tiny channels so that the drop followed a path, and if that path were mined with dried proteins and chemically triggered dyes, the thumbnail-size square could be a mini-laboratory — one that could be run off by the thousands on a Xerox machine.
Diagnostics for All, the private company Dr. Whitesides founded four years ago here in Boston’s Brighton neighborhood to commercialize his inspirations, has already created such a test for liver damage. It requires a single drop of blood, takes 15 minutes and can be read by an untrained eye: If a round spot the size of a sesame seed on the paper changes to pink from purple, the patient is probably in danger.
Using paper in diagnostic tests is not entirely new. It soaks up urine in home pregnancy kits and blood in home diabetes kits. But Dr. Whitesides has patented ways to control the flow through multiple layers for ever-more-complex diagnoses. His test has proved more than 90 percent accurate on blood samples previously screened by the laboratory of Beth Israel Deaconess Medical Center, a Harvard teaching hospital, said Una S. Ryan, chief executive of Diagnostics for All…
The initial target audience is AIDS patients with tuberculosis who must take powerful cocktails of seven or more drugs. Some drugs damage the liver, and deaths from liver failure are 12 times as common among African AIDS patients as among American ones, Dr. Ryan said, because current liver tests are expensive and require tubes of blood…
RTFA. Truly worthwhile effort, starting with grants from the Bill and Melinda Gates foundation and carrying through to government assistance both sides of the pond.
Taking the cost of tests from dollars to pennies makes them affordable in the 3rd World – as well as the growing pool of poverty in the industrial West. Many examples, many goals already met. The sort of medical research that doesn’t make billions for pharmaceutical giants; but, helps human beings worldwide.
Tiny $14 Kilobots work in self-programming swarms
Autonomous robotic devices are certainly capable of some impressive feats, but as is the case with people, sometimes large groups can accomplish what an individual or a small group can’t. Research projects such as BAE Systems’ MAST program recognize this potential, and are investigating ways in which entire swarms of small robots could work together.
The problem is, given how much time and money goes into the creation of a typical autonomous robot, it’s difficult to find a swarm of them to experiment upon – researchers often have to use computer simulations, or do their tests with a small group of robots, then scale up the results. That’s where Harvard University’s Kilobot project comes into play. It incorporates tiny swarming robots that take just five minutes to build, and that are worth about US$14 each.
Each Kilobot is powered by a rechargeable 3.4-volt lithium-ion battery, that can keep it running for at least three hours. It moves via three rigid legs that are vibrated by two motors, allowing it to move left, right or straight forward. A bottom-mounted wide-angle infrared transceiver shoots a light beam down at the smooth surfaces that the robot shimmies across, that beam reflecting up to be received by other nearby Kilobots. This lets them communicate with one another, and judge proximity to their neighbors. An onboard microcontroller allows them to act on the data they receive.
Swarms of potentially hundreds or even thousands of Kilobots can be controlled by an overhead infrared controller, that can program an unlimited number of robots simultaneously in under 40 seconds…
While the real world applications of such actions might seem limited, one has to remember that the Kilobots were designed as research tools, not as practical robots. Lessons learned with them, however, could lead to packs of robots that could explore and report on hostile environments, perform environmental monitoring, clean up hazardous materials, or various other functions.
I think William Gibson is writing copy for Harvard, nowadays.
I you may tire of this statement, I repeat myself. If I were starting out again, today, I would likely be working in computational analysis in one or another field of science. This would be a taste-tempting treat for my somewhat orderly brain.
Scientists reverse the ageing process in mice – are we next?

Scientists claim to be a step closer to reversing the ageing process after rejuvenating worn out organs in elderly mice. The experimental treatment developed by researchers at Harvard Medical School turned weak and feeble old mice into healthy animals by regenerating their aged bodies.
The surprise recovery of the animals has raised hopes among scientists that it may be possible to achieve a similar feat in humans – or at least to slow down the ageing process…
“What we saw in these animals was not a slowing down or stabilisation of the ageing process. We saw a dramatic reversal – and that was unexpected,” said Ronald DePinho, who led the study, which was published in the journal Nature.
“This could lead to strategies that enhance the regenerative potential of organs as individuals age and so increase their quality of life. Whether it serves to increase longevity is a question we are not yet in a position to answer…”
The Harvard group focused on a process called telomere shortening. Most cells in the body contain 23 pairs of chromosomes, which carry our DNA. At the ends of each chromosome is a protective cap called a telomere. Each time a cell divides, the telomeres are snipped shorter, until eventually they stop working and the cell dies or goes into a suspended state called “senescence”. The process is behind much of the wear and tear associated with ageing…
Repeating the trick in humans will be more difficult. Mice make telomerase throughout their lives, but the enzyme is switched off in adult humans, an evolutionary compromise that stops cells growing out of control and turning into cancer. Raising levels of telomerase in people might slow the ageing process, but it makes the risk of cancer soar…
DePinho said none of Harvard’s mice developed cancer after the treatment. The team is now investigating whether it extends the lifespan of mice or enables them to live healthier lives into old age.
Bravo! Another step forward for medicine, science, for human beings.
Measurements of carbon in China’s air indicate sharp reductions

Alternative sources for electrical power in China continue dynamic growth
A collaborative, six-year study of carbon dioxide (CO2) levels in Beijing and surrounding provinces suggests that combustion efficiency, a component of overall energy efficiency, is improving in the region.
The findings, published in the September 21 issue of Atmospheric Chemistry and Physics [.pdf], are generally consistent with official Chinese government statistics and could bolster their credibility as international negotiations proceed on commitments of China and other nations to combat climate change.
Which wouldn’t even be a question here if Americans realized that many other nations differentiate between agitprop and statements about commerce and science.
A team of atmospheric scientists and environmental engineers from Harvard University and Tsinghua University in Beijing have continuously measured atmospheric CO2 and carbon monoxide (CO) levels in rural Miyun, about 100 km northeast of Beijing, since November 2004…
The measurements provide the most detailed look at carbon emissions for a specific urbanized and industrialized region of China to date. Moreover, the resulting analysis of CO2 and CO levels is generally consistent with China’s official statistics, showing an upward trend in overall energy efficiency…
Over the period of study—and while controlling for daily, seasonal, and weather-induced fluctuations—the data trends indicated increasing combustion efficiency in the Beijing region. Modernization of industrial boilers, replacing old vehicles with new ones meeting stricter standards, and closing of older industrial facilities can all contribute to this trend…
While our indigenous reactionaries, anti-intellectuals and science-haters in general piss and moan about the intimidating short-term economic costs of building a healthier life for our nation, other countries, other governments press ahead with the task. Media flunkies will ignore publication of a report like this as they are supposed to. It’s kind of a chuckle that the only folks who tend to track down information like this are on the political Left – or part of the stodgy investment community.
We witnessed a perfect example of the latter, this week – with Alcoa reporting “surprising” growth and profits for the last quarter. Surprising to the average ignorant consumer, surprising to the typical American voter. But, a logical result of China shutting down Aluminum producers who wouldn’t live up to increasing requirements for cleaner air and water. Alcoa stepped in with the product needed by Chinese manufacturers – now deriving more and more from the global marketplace than domestically until native producers live up to high environmental standards.
The Harvard China Project is a research program focused on China’s atmospheric environment, collaborating across schools of Harvard University and with Chinese universities. It conducts interdisciplinary, peer-reviewed studies related to air pollution and greenhouse gases in China, designed to build knowledge and research capacities to help align China’s domestic priorities on environment and development with equitable international strategies on climate change.
Learn more in kindergarten, earn more when you grow up

Click on the photo – for a video
There isn’t a lot of research that links early childhood test scores to earnings as an adult. But new research reveals a surprising finding: Students who learn more in kindergarten earn more as adults. They are also more successful overall.
Harvard University economist John Friedman says he and a group of colleagues found that students who progress during their kindergarten year from attaining an average score on the Stanford Achievement Test to attaining a score in the 60th percentile can expect to make about $1,000 more a year at age 27 than students whose scores remain average.
Taking into account all variation across kindergarten classes, including class size, individuals who learn more–as measured by an above-average score on the Stanford Achievement Test–and are in smaller classes earn about $2,000 more per year at age 27.
Moreover, students who learn more in kindergarten are more likely to go to college than students with similar backgrounds. Those who learn more in kindergarten are also less likely to become single parents, more likely to own a home by age 28 and more likely to save for retirement earlier in their work lives…
This new study, funded by the National Science Foundation’s Division of Social and Economic Sciences, examined adult outcomes of nearly 12,000 students who took part in the original study and who are now 30 years old. It allowed the research team to go beyond what children learned during their year in the STAR project to see how their kindergarten learning experiences affected their lives.
Well, rock on, kids!
The sort of outcome I’ve expected ever since the days of the original HeadStart Programs. No wonder reactionary politicians have tried their best to squash such programs – especially among minority children.
The last thing they want is better educated voters, people with improved status in their communities – and thinking about changing the politics of the world around them.
One more let’s-sue-a-successful-geek lawsuit

A few days ago, at the Allen & Co. mogul conference in Sun Valley, Mark Zuckerberg was approached by a “fan” apparently seeking an autograph. The fan was actually a process server who handed him a lawsuit. And now we know what that lawsuit was about.
Some guy in New York state claims he owns 84% of Facebook based on a two-page “contract” he entered into with Mark Zuckerberg 7 years ago–9 months before Facebook was founded…
Now, this claim sounds (and almost certainly is) ridiculous–especially coming 7 years after the fact. But Paul Ceglia was apparently persuasive enough that a New York court has issued a temporary restraining order that bars Facebook and Mark Zuckerberg from transferring any assets.
The restraining order was filed by a state court, and state courts do occasionally go batty. Facebook has since filed to have the lawsuit transferred to a Federal court, which will probably help the company’s cause…
In his suit, Mr. Ceglia claims he signed a contract with Mr. Zuckerberg on April 28, 2003, to develop and design a website, paying a $1,000 fee but getting a 50% stake in the product. The contract stipulated that Mr. Ceglia would get an additional 1% interest in the business for every day after Jan. 1, 2004, until it was completed…a suitable website for the project Seller [Mr. Zuckerberg] has already initiated that is designed to offer the students of Harvard university [sic] access to a wesite [sic] similar to a live functioning yearbook with the working title of ‘The Face Book.’”
The contract was signed 8 months before Mark actually registered the domain thefacebook.com in January 2004.
One other fact worth mentioning: Last year, New York State Attorney General Andrew Cuomo accused Ceglia of defrauding the customers of his wood-pellet fuel company.
I hear he sells bridges in Brooklyn. And oceanfront property in Arizona.
An Ibuprofen a day might keep Parkinson’s Disease away

New research shows people who regularly take ibuprofen may reduce their risk of developing Parkinson’s disease, according to a study released February 17…
The research involved 136,474 people who did not have Parkinson’s disease at the beginning of the research. Participants were asked about their use of non-steroid anti-inflammatory drugs (NSAIDs), including aspirin, ibuprofen and acetaminophen. After six years, 293 participants had developed Parkinson’s disease.
The study found regular users of ibuprofen were 40 percent less likely to develop Parkinson’s disease than people who didn’t take ibuprofen. Also, people who took higher amounts of ibuprofen were less likely to develop Parkinson’s disease than people who took smaller amounts of the drug. The results were the same regardless of age, smoking and caffeine intake.
“Ibuprofen was the only NSAID linked to a lower risk of Parkinson’s,” said Xiang Gao, MD, with Harvard School of Public Health in Boston. “Other NSAIDs and analgesics, including aspirin and acetaminophen, did not appear to have any effect on lowering a person’s risk of developing Parkinson’s. More research is needed as to how and why ibuprofen appears to reduce the risk of Parkinson’s disease, which affects up to one million people in the United States.”
I’ll second that. I’ve seen a few folks waste away via Parkinson’s. Terribly frustrating ailment.
I don’t really understand why; but, some of the anti-medicine, anti-science crowd, have more of a hard-on for Ibuprofen than just about any other OTC medication. Some cranky creaky old geeks wouldn’t get through the day without it.
Like me.





