Tagged: Randy Lewis

Scientists GM silkworms to produce artificial spider silk

A research and development effort…has succeeded in producing transgenic silkworms capable of spinning artificial spider silks.

“This research represents a significant breakthrough in the development of superior silk fibers for both medical and non-medical applications,” said Malcolm J. Fraser Jr…. “The generation of silk fibers having the properties of spider silks has been one of the important goals in materials science.”

Natural spider silks have a number of unusual physical properties, including significantly higher tensile strength and elasticity than naturally spun silkworm fibers. The artificial spider silks produced in these transgenic silkworms have similar properties of strength and flexibility to native spider silk.

Silk fibers have many current and possible future biomedical applications, such as use as fine suture materials, improved wound healing bandages, or natural scaffolds for tendon and ligament repair or replacement. Spider silk-like fibers may also have applications beyond biomedical uses, such as in bulletproof vests, strong and lightweight structural fabrics, a new generation athletic clothing and improved automobile airbags…

Fraser, with the assistance of University of Wyoming researcher Randy Lewis, a biochemist who is one of the world’s foremost authorities on spider silk, and Don Jarvis, a noted molecular geneticist who specializes in insect protein production, genetically engineered silkworms in which they incorporated specific DNAs taken from spiders…

Since silkworms are already a commercially viable silk production platform, these genetically engineered silkworms effectively solve the problem of large scale production of engineered protein fibers in an economically practical way.

Bravo! I doubt if we even have to worry about vegan Luddites fretting over people eating these silkworms.

Cripes. Materials engineers/structural designers will be having a ball.

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