Antibiotics stewardship reduces rate of hospital readmission for children

Among 176 children treated for nonchronic complex care issues and without underlying medical conditions, none were readmitted within 30 days if the physician accepted the recommendation of the pharmacist-physician antibiotics stewardship team, reported Jason Newland, MD, of Children’s Mercy Hospital-Kansas City in Missouri, and colleagues.

In comparison, among the 88 children whose doctors rejected the recommendations, 3.4% required readmission, they said at the annual IDWeek conference.

Newland noted that the difference was statistically significant

The pattern was similar among children who had chronic complex care issues. Of the 149 children whose doctors accepted the recommendations regarding use of antibiotics, there was no 30-day readmission. However, among the children whose doctors said No to the recommendations, the readmission rate was 2.6%, Newland said.

“We are only talking about two or three new admissions,” he acknowledged, “but there was none” in the groups where the recommendations were explained and were accepted by the doctors.

Pranita Tamma, MD, who moderated the IDWeek press briefing where the study results were presented, told MedPage Today that “antimicrobial stewardship programs generally consist of a physician and a pharmacist who oversee, guide, and educate clinicians in their institutions about the appropriate use of antibiotics. The goal of every stewardship program in the U.S. is to ensure that every patient who requires an antibiotic receives the right drug, the right dose, by the right route, and for the right duration of time.”

Dr. Pranita Tamma noted for the press briefing – “Ultimately, we believe that this improves the care of children while decreasing the unintended consequences of antibiotic overuse, including allergic reactions, severe diarrheal illnesses, hearing loss, kidney and liver damage, and, of course, antibiotic resistance.”

Hear, hear.

One thought on “Antibiotics stewardship reduces rate of hospital readmission for children

  1. Geophagist says:

    “Scientists have discovered a new group of antibiotics that may be able to kill drug-resistant bacteria and germs.” http://theweek.com/speedreads/index/274674/speedreads-this-dirt-made-antibiotic-could-kill-drug-resistant-germs
    “The new drug, teixobactin, is created from bacteria that live in dirt and has been tested in lab experiments. Researchers described the antibiotic in a study published in the journal Nature on Wednesday, saying it is unlikely bacteria will become resistant to it. The researchers created teixobactin by studying 10,000 strains of bacteria that live in soil and growing them in their natural dirt habitat. The scientists then isolated compounds from the bacteria, testing them alongside bacteria that cause disease. While most antibiotics target proteins in bacteria, Live Science explains, teixobactin kills bacteria by breaking down fat molecules on the cell walls, making it more difficult to develop resistance.” Includes links to journal Nature and Live Science articles.
    According to the authors of “A new antibiotic kills pathogens without detectable resistance” in the journal Nature article “Most antibiotics were produced by screening soil microorganisms, but this limited resource of cultivable bacteria was overmined by the 1960s. Synthetic approaches to produce antibiotics have been unable to replace this platform. Uncultured bacteria make up approximately 99% of all species in external environments, and are an untapped source of new antibiotics.”

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