Lead exposure in mothers can affect more than one generation

A team of researchers at Wayne State University have discovered that mothers with high levels of lead in their blood not only affect the fetal cells of their unborn children, but also their grandchildren. Their study, Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren, was published online this week in Scientific Reports.

It’s a known fact that babies in the womb can be affected by low levels of lead exposure. If a pregnant woman is exposed to lead, the lead passes through the placenta into the baby’s developing bones and other organs. Pregnant women with a past exposure to lead can also affect the unborn child’s brain, causing developmental problems later in life. Previous research studies have suggested that exposure to heavy metal toxicants can influence a person’s global DNA methylation profile.

In the recent Wayne State study led by Douglas Ruden, Ph.D….program leader in the Center for Urban Responses to Environmental Stressors, he and his research team revealed that lead exposure can cause specific changes in DNA methylation, which can be detected in dried blood spots beyond one generation. The neonatal blood spots from both the mothers and children in this study were obtained from the Michigan Neonatal Biobank, a unique resource that has most of the neonatal dried blood spots from children born in Michigan since 1984…

“Our results suggest that lead exposure during pregnancy affects the DNA methylation status of the fetal germ cells, which leads to altered DNA methylation in grandchildren’s neonatal dried blood spots,” said Ruden. “This is the first demonstration that an environmental exposure in pregnant mothers can have an epigenetic effect on the DNA methylation pattern in the grandchildren.”

The research team stated that this novel, two-generational study design might be able to identify the genes that may serve as possible candidate biomarkers for future transgenerational risk assessment studies.

Consider the creeps who despoil the world’s environment in their quest for short-term profits not only may be shortening your own life; but, that of your children – and, now, we know the effects may proceed directly to your grandchildren.

And the contaminated environment hangs around even longer.

The US “leads” the solar energy revolution by laying off solar energy researchers

On Monday, Oct. 5, Stuart Farrell had planned to take the morning off from his job as a researcher at the National Renewable Energy Laboratory in Golden, Colo., after being awake all night taking care of his sick 2-year-old son. But at 10:30 a.m., he received a call asking him to come in for an 11:30 meeting…

Farrell, who had worked in solar energy research at the laboratory for two and a half years, was one of 15 solar research staff members laid off that day due to federal funding cuts, according to NREL public affairs manager George Douglas. And another 40 to 60 staff members are expected to be lost through a voluntary separation program that the lab will initiate on Oct. 12.

Almost all of the researchers already laid off were involved in “next generation,” or long-term, solar research, Douglas said. Farrell’s work, for instance, involved research on improving the efficiency of cadmium telluride solar cells.

It’s the latest sign of a trend that experts say is undermining U.S. efforts to promote alternative energy: Federal funding for solar energy research has declined steadily over the past several years, despite emphasis from the Obama administration on continued investment in research and development of clean energy technologies. These cuts have affected the federal solar program at large, not just solar research at NREL…

“NREL is actually one of the smallest of the national laboratories, and I think it’s been one that has had one of the largest impacts of any of the national laboratories,” said Al Compaan, president and CTO of Lucintech, a company involved in the development of photovoltaic modules. “I’m particularly pained to see any further cuts in funding [to NREL].” For instance, support from NREL was integral to the success of photovoltaic manufacturer First Solar, which Compaan referred to as “one of the bright shining stars in the success of federal government support for solar energy.”…

Yet the budget appropriations have fallen short of the requests over the past few years, and applied research, particularly on long-term, forward-looking technologies like the project Farrell was involved with at NREL, has been one of the areas to suffer. The reasons for the funding cuts could be tied to budget sequestration, or limits on the size of the federal budget, which can force spending cuts in certain areas in order to bring the total budget down…

Despite these reductions, solar energy itself has continued to expand and contribute to decarbonization in the U.S., at least partly thanks to the importation of solar modules from other nations, particularly China. The U.S. market share in photovoltaic manufacturing has dropped significantly since the late 90s, and China has become the major source of module shipments over the past five years…

Jobs, jobs, jobs – the mantra of political hacks from both parties. But, as long as the government is run by an amalgamation of reactionaries and cowards the inevitability of change continues to be driven by the nations with a real dedication to alternative energy.

President Obama can blather all he wants at press conferences celebrating his joint energy and environment agreements with President Xi. At the rate we’re going the only American jobs flowing from the solar revolution will be as installers. Manufacturing for domestic consumption – much less export – will continue to diminish in a nation that would rather dedicate research to new and exciting weapons of mass destruction.

Our politicians take Americans another step backwards – bowing to the Koch Brothers and the fossil fuel empire.