Clinical trials tend to be positive when Docs get industry dollar$

When study investigators have financial relationships with pharmaceutical companies, clinical trial results are more likely to turn up positive…

In a review of 190 papers on randomized controlled trials, taking money from industry was significantly associated with favorable trial results in a fully adjusted model…Salomeh Keyhani, MD, of the University of California San Francisco, and colleagues reported online…

Their findings suggest bias in the evidence base, Keyhani said. Practicing clinicians “should be concerned enough to employ healthy skepticism while reviewing the results of any one trial,” she told MedPage Today.

❝ The paper makes the distinction between a study being funded by a drug company, and investigators who have financial relationships with those companies.

Researchers with financial relationships can influence the study results in less obvious ways, such as study design and analytic approach, but Keyhani noted that the current research is a “cross-sectional study so any interpretation of the findings should be made with caution.”…

Gasp! Who’da thunk it.

RTFA for methodology – and more.

One thought on “Clinical trials tend to be positive when Docs get industry dollar$

  1. List of X says:

    There’s a method called p-hacking where researchers run multiple trials and publish the results for the trial that produces the most statistically significant results. I’m not surprised that researchers paid by industry are more tempted to use the method.

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