Most reliable individual model = Audi Q5 SUV
1. Toyota
2. Acura
3. Hyundai
4. Honda
5. Mitsubishi
6. Subaru
7. Buick
8. Mercedes
9. Lexus
10. Nissan
NOTE Between Oct. 1, 2017 and Sept. 20, 2018, CarMD said it measured and analyzed vehicle data and health of about 5.6 million in-use vehicles manufactured from 1996 to 2018 reporting check engine health.
Lots of different ways to approach these questions and the article does a decent job, ranging from repair and maintenance costs to repair frequency, etc.. RTFA.