Trump loves those steroids

…Confusion continued Sunday about the severity of Mr. Trump’s condition, as his physician revealed the president had been given a dose of a powerful steroid that the World Health Organization has recommended for patients who are “critically ill” with COVID-19.

Dr. Sean Conley, the White House physician, said the president had been given dexamethasone, on Saturday, and had experienced two drops in his oxygen levels since the onset of the illness. Dexamethasone has been shown to improve outcomes for patients with severe cases of COVID-19, including those who require supplemental oxygen, but is not recommended for use in patients with milder cases.

“Dexamethasone is a very potent steroid that can have brain effects. There can be a manic behavior associated with dexamethasone, so certainly important that we understand that,” CBS News medical contributor Dr. David Agus said after the briefing.

6 thoughts on “Trump loves those steroids

  1. Showboating says:

    ‘That should never have happened’: Inside Trump’s Walter Reed parade https://www.cnn.com/2020/10/05/politics/trump-secret-service-trip/index.html
    ‘This is insanity’: Walter Reed physician among critics of Donald Trump drive-by visit https://www.theguardian.com/us-news/2020/oct/04/trump-walter-reed-drive-by-visit-criticism
    Imagine having a literal COVID parade’: Critics react after Trump leaves Walter Reed to see supporters https://www.usatoday.com/story/news/politics/2020/10/04/trump-drives-by-walter-reed-supporters-reaction/3619529001/
    QAnon supporters push baseless theory that Trump isn’t in the hospital https://www.politifact.com/factchecks/2020/oct/04/facebook-posts/qanon-supporters-push-baseless-theory-trump-isnt-h/

  2. AAAARGH! says:

    Donald J. Trump @realDonaldTrump 12:37 PM · Oct 5, 2020:
    “I will be leaving the great Walter Reed Medical Center today at 6:30 P.M. Feeling really good! Don’t be afraid of Covid. Don’t let it dominate your life. We have developed, under the Trump Administration, some really great drugs & knowledge. I feel better than I did 20 years ago!”

    • Doc says:

      Nearly a third of hospitalized COVID-19 patients experienced some type of altered mental function — ranging from confusion to delirium to unresponsiveness — in the largest study to date of neurological symptoms among coronavirus patients in a U.S. hospital system. (NYT) https://www.boston.com/news/coronavirus/2020/10/05/one-third-covid-patients-altered-mental-state-study After they were discharged, only 32% of the patients with altered mental function were able to handle routine daily activities like cooking and paying bills.
      About 4 out of 5 patients hospitalized with Covid-19 suffer neurologic symptoms such as muscle pain, headaches, confusion, dizziness and the loss of smell or taste, new research shows. (Bloomberg) https://www.bloomberg.com/news/articles/2020-10-05/neurologic-symptoms-found-in-4-of-5-hospitalized-covid-patients
      The most severe condition listed was encephalopathy, “characterized by altered mental function ranging from mild confusion to coma,” said Igor Koralnik, the chief of neuro-infectious disease at Northwestern Medicine in Chicago and one of the study’s authors.
      Patients with altered mental function — the medical term is encephalopathy — were also nearly seven times as likely to die as those who did not have that type of problem.
      “Encephalopathy is a generic term meaning something’s wrong with the brain,” Koralnik said. The description can include problems with attention and concentration, loss of short-term memory, disorientation, stupor and “profound unresponsiveness,” or a comalike level of consciousness.

  3. 4therecord says:

    “President Donald Trump previously reported he earned capital gains from Regeneron Pharmaceuticals and Gilead Sciences Inc., the manufacturers of two of the medicines he’s taken as part of his COVID-19 treatment plan.” https://www.usatoday.com/story/money/2020/10/03/trump-walter-reed-treatment-president-regeneron-gilead-remdesivir/3610111001/
    “According to a 2017 financial disclosure form filed with the U.S. Office of Government Ethics in June 2017, Trump had a capital gain of $50,001 to $100,000 for Regeneron Pharmaceuticals and $100,001 to $1 million for Gilead Sciences Inc. The form notes the information was of April 15, 2017.
    Trump’s subsequent disclosure forms, including his 2020 form signed July 31, did not list Regeneron or Gilead.
    Trump received a single 8-gram dose of Regeneron’s polyclonal antibody cocktail as a precautionary measure, according to his physician Sean Conley. The antibody cocktail is in four late-stage clinical trials, and its safety and efficacy have not been fully evaluated by any regulatory authority, the company said on its webpage.”

  4. Running amok says:

    ‘Roid rage’ Trump crashes markets by tweeting that there will be NO stimulus until after election – as doctor voices fear his COVID medication causes mania, aggression and psychosis (Daily Mail UK) https://www.dailymail.co.uk/news/article-8811961/Roid-rage-Trump-crashes-markets-tweeting-NO-stimulus-election.html
    “…Research has shown that just a few days on dexamethasone can leave patients with memory and cognitive deficits. Corticosteroids – the class of drugs dexamethasone belongs to – may cause psychiatric side effects in anywhere from 1.8 to 57 percent of patients taking them.
    Experts’ first worry was that the use of dexamethasone to treat Trump suggested he was very sick, since the $6 steroid may be dangerous to people with mild COVID-19.
    But because it’s been linked to everything from mania to memory problems, and aggression to psychosis, some are also concerned that the president’s judgement could be impaired as he reportedly continues to work through his illness.
    Ending stimulus talks however goes deep into the most damaging territory possible for a president whose only path to re-election had been on high stock market numbers and a belief in his economic record among swing state voters.”
    Se also Mayo Clinic: “Psychiatric Adverse Effects of Corticosteroids” https://www.mayoclinicproceedings.org/article/S0025-6196(11)61160-9/fulltext

  5. Doc says:

    In a study it described as both conclusive and disappointing, the World Health Organization said the antiviral drug remdesivir has “little or no effect on mortality” for patients hospitalized with coronavirus and it doesn’t seem to help patients recover any faster, either.
    Until now, remdesivir has been the only drug that appeared to have specific effects for coronavirus. It was the only drug with an Emergency Use Authorization for Covid-19 from the US Food and Drug Administration. https://www.cnn.com/2020/10/15/health/remdesivir-covid-who-trial-mortality/index.html
    Remdesivir and interferon fall flat in WHO’s megastudy of COVID-19 treatments https://www.sciencemag.org/news/2020/10/remdesivir-and-interferon-fall-flat-who-s-megastudy-covid-19-treatments
    Scientists at the World Health Organization (WHO) released the data as a preprint on medRxiv last night ahead of its planned publication in the New England Journal of Medicine. https://www.medrxiv.org/content/10.1101/2020.10.15.20209817v1

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