Unaffected by Covid? Maybe thank your Neanderthal ancestors

People who survive a bout of Covid-19 with mild symptoms or even no symptoms may be able to thank their Neanderthal ancestors, a new study suggests.

Researchers found a genetic mutation that reduces the risk of severe Covid-19 infection by about 22%. It was found in all the samples they took of Neanderthal DNA, and in about 30% of samples from people of European and Asian origin.

The genetic region involved affects the body’s immune response to RNA viruses such as the coronavirus, as well as West Nile virus and hepatitis C virus, the researchers reported Tuesday in the Proceedings of the National Academy of Sciences…

The finding could help explain why Black patients are so much more likely to suffer severe coronavirus disease. Neanderthals, who went extinct about 40,000 years ago, lived alongside and sometimes interbred with modern humans in Europe and Asia but not in Africa, and people of purely African descent do not carry Neanderthal DNA. Studies estimate that about 2% of DNA in people of European and Asian descent can be traced back to Neanderthals.

RTFA. Details on the research. And it’s certainly interesting to our household. Genetic analysis shows my wife with about 2% Neanderthal DNA. I’m actually at about 3%.